CRISPR-CAS9 IN GENE THERAPY

Journal «Language & Science» UTMN.


Release:

№8 2019. 03.00.00 БИОЛОГИЧЕСКИЕ НАУКИ

Title: 
CRISPR-CAS9 IN GENE THERAPY


About the authors:

Sagalakova Viktoriya Viktorovna, Specialist student, University of Tyumen, stud0000215666@study.utmn.ru
Garkusha Nadezhda Anatolievna,

Candidate of Pedagogic Sciences, University of Tyumen, Institute of Mathematics and Computer Sciences, Foreign Languages and Intercultural Professional Communication Department, Associate Professor, n.a.garkusha@utmn.ru


Abstract:

This article is about gene-editing tool CRISPR-Cas9 for altering the genome of human. The main purpose of the article is to collect and provide information about application of this system for the therapy of different diseases and identify bioethical side of this method.

References:

1. Scientists Erase Heart Disease Defect in Human Embryos https://www.livescience.com/59971-crispr-used-on-embryos-in-us.html
2. CRISPR-Cas9 for in vivo Gene Therapy: Promise and Hurdles. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023403/
3. Guangdong releases preliminary investigation result of gene-edited babies http://www.xinhuanet.com/english/2019-01/21/c_137762633.htm
4. Chinese Scientist Who Claimed to Make Genetically Edited Babies Is Kept Under Guard https://www.nytimes.com/2018/12/28/world/asia/he-jiankui-china-scientist-gene-editing.html
5. What Is CRISPR? https://www.livescience.com/58790-crispr-explained.html
6. The new frontier of genome engineering with CRISPR-Cas9 https://science.sciencemag.org/content/346/6213/1258096
7. Everything You Need to Know About CRISPR-Cas9 https://www.synthego.com/learn/crispr
8. Bioethics in genetic engineering https://www.ncbi.nlm.nih.gov/pubmed/11885124
9. Bioethics https://www.iep.utm.edu/bioethic/#SH3b